9LJ5
Human KCNQ5-CaM-PIP2-HN37 complex in an open conformation.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, B, D, G) | Potassium voltage-gated channel subfamily KQT member 5 | polymer | 626 | 70463.3 | 4 | UniProt (Q9NR82) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) | Homo sapiens (human) | KQT-like 5,Potassium channel subunit alpha KvLQT5,Voltage-gated potassium channel subunit Kv7.5 |
| 2 | B, D, F, H (E, C, F, H) | Calmodulin-3 | polymer | 177 | 19615.4 | 4 | UniProt (P0DP25) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, K, L, M, O... (A, B, D, G) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 8 | Chemie (PIO) | |||
| 4 | J, N, Q, R (A, B, D, G) | methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate | non-polymer | 340.4 | 4 | Chemie (9MF) |
Sequence modifications
A, B, D, G: 90 - 698 (UniProt: Q9NR82)
E, C, F, H: 1 - 149 (UniProt: P0DP25)
| PDB | External Database | Details |
|---|---|---|
| Met 89 | - | initiating methionine |
| Leu 699 | - | expression tag |
| Glu 700 | - | expression tag |
| Gly 701 | - | expression tag |
| Gly 702 | - | expression tag |
| Ser 703 | - | expression tag |
| Ser 704 | - | expression tag |
| Gly 705 | - | expression tag |
| Gly 706 | - | expression tag |
| Trp 707 | - | expression tag |
| Ser 708 | - | expression tag |
| His 709 | - | expression tag |
| Pro 710 | - | expression tag |
| Gln 711 | - | expression tag |
| Phe 712 | - | expression tag |
| Glu 713 | - | expression tag |
| Lys 714 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 150 | - | expression tag |
| Glu 151 | - | expression tag |
| Gly 152 | - | expression tag |
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Ser 155 | - | expression tag |
| Gly 156 | - | expression tag |
| Gly 157 | - | expression tag |
| Leu 158 | - | expression tag |
| Val 159 | - | expression tag |
| Pro 160 | - | expression tag |
| Arg 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Ser 163 | - | expression tag |
| Gly 164 | - | expression tag |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Ser 167 | - | expression tag |
| Gly 168 | - | expression tag |
| Gly 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 360314.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 7334.1 | |
| All* | Total formula weight | 367649.0 |
