9LIH
Cryo-EM structure of Saccharomyces cerevisiae Mitochondrial Respiratory Complex II in cyclobutrifluram-bound state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | polymer | 596 | 65699.0 | 1 | UniProt (Q00711) Pfam (PF00890) Pfam (PF02910) | Saccharomyces cerevisiae S288C | Flavoprotein subunit of complex II,FP |
| 2 | B (B) | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | polymer | 237 | 27164.5 | 1 | UniProt (P21801) Pfam (PF13085) Pfam (PF13534) | Saccharomyces cerevisiae S288C | Iron-sulfur subunit of complex II,Ip |
| 3 | C (C) | Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial | polymer | 144 | 16396.1 | 1 | UniProt (P33421) Pfam (PF01127) | Saccharomyces cerevisiae S288C | |
| 4 | D (D) | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | polymer | 131 | 14441.6 | 1 | UniProt (P37298) Pfam (PF05328) | Saccharomyces cerevisiae S288C | CybS,Succinate-ubiquinone reductase membrane anchor subunit |
| 5 | E (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 6 | F (B) | ~{N}-[(1~{S},2~{S})-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)pyridine-3-carboxamide | non-polymer | 389.2 | 1 | Chemie (A1EKU) | |||
| 7 | G (B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 8 | H (B) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 9 | I (B) | FE3-S4 CLUSTER | non-polymer | 295.8 | 1 | Chemie (F3S) | |||
| 10 | J (D) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 1 | Chemie (PEE) |
Sequence modifications
C: 55 - 198 (UniProt: P33421)
D: 37 - 167 (UniProt: P37298)
| PDB | External Database | Details |
|---|---|---|
| Arg 74 | Lys 74 | variant |
| Phe 95 | Leu 95 | variant |
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | Glu 123 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 123701.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2742.0 | |
| All* | Total formula weight | 126443.3 |
