9LHC
human alpha 7 nicotinic acetylcholine receptor in complex with L-nicotine (meta-two-nicotine-bound desensitized state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Neuronal acetylcholine receptor subunit alpha-7 | polymer | 512 | 57616.3 | 5 | UniProt (P36544) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 2 | F, G, H, I, J (F, G, H, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 3 | K, N (A, C) | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE | non-polymer | 162.2 | 2 | Chemie (NCT) | |||
| 4 | L, M, O, P, Q (A, B, C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 5 | R, S (B, D) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 502 (UniProt: P36544)
| PDB | External Database | Details |
|---|---|---|
| Gly 503 | - | expression tag |
| Gly 504 | - | expression tag |
| Asp 505 | - | expression tag |
| Tyr 506 | - | expression tag |
| Lys 507 | - | expression tag |
| Asp 508 | - | expression tag |
| Asp 509 | - | expression tag |
| Asp 510 | - | expression tag |
| Asp 511 | - | expression tag |
| Lys 512 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 288081.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2122.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1430.5 | |
| All* | Total formula weight | 291633.8 |
