9LGC

bovine ABCC1 bound to vincristine and GSH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Multidrug resistance-associated protein 1	polymer	1558	175004.7	1	UniProt (Q8HXQ5) Pfam (PF24357) Pfam (PF00664) Pfam (PF00005)	Bos taurus (domestic cattle)	ATP-binding cassette sub-family C member 1,Glutathione-S-conjugate-translocating ATPase ABCC1,Leukotriene C(4) transporter,LTC4 transporter
2	B (A)	GLUTATHIONE	non-polymer		307.3	1	Chemie (GSH)
3	C, D (A)	vincristine	non-polymer		825.0	2	Chemie (R1Q)

Sequence modifications

A: 1 - 1530 (UniProt: Q8HXQ5)

PDB	External Database	Details
Lys 1531	-	expression tag
Leu 1532	-	expression tag
Gly 1533	-	expression tag
Ser 1534	-	expression tag
Glu 1535	-	expression tag
Asn 1536	-	expression tag
Leu 1537	-	expression tag
Tyr 1538	-	expression tag
Phe 1539	-	expression tag
Gln 1540	-	expression tag
Gly 1541	-	expression tag
Gly 1542	-	expression tag
Ser 1543	-	expression tag
Gly 1544	-	expression tag
Gly 1545	-	expression tag
Ser 1546	-	expression tag
Gly 1547	-	expression tag
His 1548	-	expression tag
His 1549	-	expression tag
His 1550	-	expression tag
His 1551	-	expression tag
His 1552	-	expression tag
His 1553	-	expression tag
His 1554	-	expression tag
His 1555	-	expression tag
His 1556	-	expression tag
His 1557	-	expression tag
His 1558	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	175004.7
Non-Polymers*	Number of molecules	3
	Total formula weight	1957.2
All*	Total formula weight	176961.9

*Water molecules are not included.