9LFD

Cryo-EM structure of human bradykinin receptor B2R bound to antagonist Win64338

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	B2 bradykinin receptor,Kappa-type opioid receptor	polymer	365	41577.1	1	UniProt (P30411) UniProt (P41145) Pfam (PF00001)	Homo sapiens (human)	B2R,BK-2 receptor,K-OR-1,KOR-1
2	B (C)	Nanobody 6	polymer	133	14730.3	1		Lama glama
3	C (A)	Win64338	non-polymer		712.0	1	Chemie (A1EJK)

Sequence modifications

A: 29 - 252 (UniProt: P30411)

PDB	External Database	Details
Lys 144	Ser 144	engineered mutation
Trp 146	Cys 146	engineered mutation

A: 253 - 282 (UniProt: P41145)
A: 283 - 393 (UniProt: P30411)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56307.3
Non-Polymers*	Number of molecules	1
	Total formula weight	712.0
All*	Total formula weight	57019.4

*Water molecules are not included.