9LFC
Cryo-EM structure of human bradykinin receptor B1R bound to antagonist R715
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B1 bradykinin receptor,Kappa-type opioid receptor | polymer | 340 | 38958.9 | 1 | UniProt (P46663) UniProt (P41145) Pfam (PF00001) | Homo sapiens (human) | B1R,BK-1 receptor,K-OR-1,KOR-1 |
| 2 | B (C) | Nanobody 6 | polymer | 171 | 18816.0 | 1 | Lama glama | ||
| 3 | C (B) | R715 | polymer | 10 | 1126.3 | 1 | synthetic construct |
Sequence modifications
A: 2 - 231 (UniProt: P46663)
A: 232 - 255 (UniProt: P41145)
A: 256 - 341 (UniProt: P46663)
| PDB | External Database | Details |
|---|---|---|
| Lys 124 | Ser 124 | engineered mutation |
| Cys 132 | Ser 132 | engineered mutation |
A: 256 - 341 (UniProt: P46663)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58901.3 | |
| All* | Total formula weight | 58901.3 |
