9LFA
Cryo-EM structure of human bradykinin receptor B1R bound to antagonist ELN441958
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B1 bradykinin receptor,Kappa-type opioid receptor | polymer | 340 | 38958.9 | 1 | UniProt (P46663) UniProt (P41145) Pfam (PF00001) | Homo sapiens (human) | B1R,BK-1 receptor,K-OR-1,KOR-1 |
| 2 | B (C) | Nanobody 6 | polymer | 171 | 18816.0 | 1 | Lama glama | ||
| 3 | C (A) | 7-chloranyl-2-[3-[(9-pyridin-4-yl-3,9-diazaspiro[5.5]undecan-3-yl)carbonyl]phenyl]-3H-isoindol-1-one | non-polymer | 501.0 | 1 | Chemie (A1EJF) |
Sequence modifications
A: 2 - 231 (UniProt: P46663)
A: 232 - 255 (UniProt: P41145)
A: 256 - 341 (UniProt: P46663)
| PDB | External Database | Details |
|---|---|---|
| Lys 124 | Ser 124 | engineered mutation |
| Cys 132 | Ser 132 | engineered mutation |
A: 256 - 341 (UniProt: P46663)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57775.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 501.0 | |
| All* | Total formula weight | 58276.0 |
