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9LBE

Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC Y251A mutant at pH 2.5 in ioooo conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Proton-gated ion channelpolymer31235607.05UniProt (Q7NDN8)
Pfam (PF02931)
Gloeobacter violaceusGLIC,Ligand-gated ion channel,LGIC
2BA, F, L, Q, W
(E, A, B, C, D)
CHLORIDE IONnon-polymer35.55Chemie (CL)
PubChem (312)
3AA, CA, DA, EA, G...
(E, A, B, C, D)
1,2-dioleoyl-sn-glycero-3-phosphoethanolaminenon-polymer744.021Chemie (PEE)
PubChem (108229)
PubChem (44891344)
PubChem (54095275)
PubChem (14238554)
PubChem (5909904)
PubChem (9546757)
PubChem (6437392)
PubChem (99655478)
PubChem (99655479)
PubChem (9546744)
PubChem (138113035)
PubChem (171729549)
Sequence modifications
A, B, C, D, E: 5 - 316 (UniProt: Q7NDN8)
PDBExternal DatabaseDetails
Ala 251Tyr 293engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight178035.0
Non-Polymers*Number of molecules26
Total formula weight15802.0
All*Total formula weight193837.0
*Water molecules are not included.

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PDB entries from 2026-05-06

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