9LB5

mutant S483T/G490N/V492M/S497T/A599G of HEV-1 E2s domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Secreted protein ORF2	polymer	148	15837.7	2	UniProt (P29326)	Hepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1)	ORF2s
2	B (B)	Secreted protein ORF2	polymer	148	15871.7	1	UniProt (P29326)	Hepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1)	ORF2s
3	D (D)	Secreted protein ORF2	polymer	148	15823.6	1	UniProt (P29326)	Hepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1)	ORF2s
4	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
5	N, O, P, Q (A, B, C, D)	water	water		18.0	811	Chemie (HOH)

Sequence modifications

A, C: 459 - 606 (UniProt: P29326)

PDB	External Database	Details
Thr 483	Ser 483	engineered mutation
Asn 490	Gly 490	engineered mutation
Met 492	Val 492	engineered mutation
Thr 497	Ser 497	engineered mutation
Gly 599	Ala 599	engineered mutation

B: 459 - 606 (UniProt: P29326)

PDB	External Database	Details
Thr 483	Ser 483	engineered mutation
Asn 490	Gly 490	engineered mutation
Met 492	Val 492	engineered mutation
Thr 497	Ser 497	engineered mutation
Phe 500	Leu 500	conflict
Gly 599	Ala 599	engineered mutation

D: 459 - 606 (UniProt: P29326)

PDB	External Database	Details
Thr 483	Ser 483	engineered mutation
Asn 490	Gly 490	engineered mutation
Met 492	Val 492	engineered mutation
Thr 497	Ser 497	engineered mutation
Ser 517	Thr 517	conflict
Gly 599	Ala 599	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63370.7
Non-Polymers*	Number of molecules	9
	Total formula weight	864.6
All*	Total formula weight	64235.2

*Water molecules are not included.