9LAD

Crystal structure of the complex between Neuronal Pentraxin 2 (NP2 PTX) and antibody fragment VHH N1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	N1 VHH	polymer	126	13840.2	1		Vicugna pacos
2	B (C)	Neuronal pentraxin-2	polymer	219	24431.7	1	UniProt (P97738) Pfam (PF00354)	Homo sapiens (human)	NP2,Neuronal activity-regulated pentraxin,Neuronal pentraxin II,NP-II
3	C (B)	AZIDE ION	non-polymer		42.0	1	Chemie (AZI)
4	D, E (C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	F, H (C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	G (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	I, J (B, C)	water	water		18.0	125	Chemie (HOH)

Sequence modifications

C: 2 - 210 (UniProt: P97738)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 211	-	expression tag
Ala 212	-	expression tag
Ala 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38271.9
Non-Polymers*	Number of molecules	6
	Total formula weight	285.2
All*	Total formula weight	38557.1

*Water molecules are not included.