9L93
Crystal structure of NCOA4 in complex with HERC2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase HERC2 | polymer | 164 | 18351.9 | 2 | UniProt (O95714) Pfam (PF11515) | Homo sapiens (human) | HECT domain and RCC1-like domain-containing protein 2,HECT-type E3 ubiquitin transferase HERC2 |
| 2 | C, D (C, D) | Nuclear receptor coactivator 4 | polymer | 51 | 5780.6 | 2 | UniProt (Q13772) | Homo sapiens (human) | NCoA-4,Androgen receptor coactivator 70 kDa protein,70 kDa AR-activator,70 kDa androgen receptor coactivator,Androgen receptor-associated protein of 70 kDa,Ferritin cargo receptor NCOA4,Ret-activating protein ELE1 |
| 3 | E, F (C, D) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 505 | Chemie (HOH) |
Sequence modifications
A, B: 2539 - 2700 (UniProt: O95714)
C, D: 395 - 442 (UniProt: Q13772)
| PDB | External Database | Details |
|---|---|---|
| Gly 2537 | - | expression tag |
| Ala 2538 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 392 | - | expression tag |
| Ala 393 | - | expression tag |
| Met 394 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48265.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 351.6 | |
| All* | Total formula weight | 48616.6 |
