9L90
The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and AMP-PCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ryanodine receptor 3 | polymer | 218 | 24993.6 | 4 | UniProt (Q15413) Pfam (PF02026) | Homo sapiens (human) | RYR-3,RyR3,Brain ryanodine receptor-calcium release channel,Brain-type ryanodine receptor,Type 3 ryanodine receptor |
| 2 | E, G (A, B) | Dantrolene | non-polymer | 314.3 | 2 | Chemie (U1C) | |||
| 3 | F, H (A, B) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 2 | Chemie (ACP) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 845 - 1062 (UniProt: Q15413)
| PDB | External Database | Details |
|---|---|---|
| Asn 846 | Gln 846 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99974.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1638.9 | |
| All* | Total formula weight | 101613.3 |
