9L7N

PEDV 3CLpro mutant (C144A) in complex with nsp12/13 peptite substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ORF1ab polyprotein	polymer	308	33705.1	2	UniProt (A0A023J7B5)	Porcine epidemic diarrhea virus
2	C, D (C, D)	Replicase polyprotein 1ab	polymer	6	645.8	2		Porcine epidemic diarrhea virus
3	E, F, G (A, B, C)	water	water		18.0	111	Chemie (HOH)

Sequence modifications

A, B: 1 - 299 (UniProt: A0A023J7B5)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 144	Cys 3141	engineered mutation
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	68701.7
All*	Total formula weight	68701.7

*Water molecules are not included.