9L78

Crystal structure of nucleotide-free human kinesin-1 motor domain (G234A mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kinesin-1 heavy chain	polymer	342	38306.0	2	UniProt (P33176) Pfam (PF00225)	Homo sapiens (human)	Conventional kinesin heavy chain,Ubiquitous kinesin heavy chain,UKHC
2	C (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B: 2 - 336 (UniProt: P33176)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ser 7	Cys 7	conflict
Ala 65	Cys 65	conflict
Ala 168	Cys 168	conflict
Ser 174	Cys 174	conflict
Ala 234	Gly 234	engineered mutation
Ala 294	Cys 294	conflict
Ser 330	Cys 330	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76611.9
All*	Total formula weight	76611.9

*Water molecules are not included.