9L5Q
Crystal structure of PI5P4Kalpha N251S in apo form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | polymer | 453 | 51277.1 | 1 | UniProt (P48426) Pfam (PF01504) | Homo sapiens (human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-Phosphate 4-Kinase,PI5P4Kalpha,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PI(5)P 4-kinase type II alpha,PIP4KII-alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha |
| 2 | B, C, D, E (A) | BORIC ACID | non-polymer | 61.8 | 4 | Chemie (BO3) | |||
| 3 | F (A) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A: 1 - 406 (UniProt: P48426)
| PDB | External Database | Details |
|---|---|---|
| Met -46 | - | initiating methionine |
| Gly -45 | - | expression tag |
| Ser -44 | - | expression tag |
| Ser -43 | - | expression tag |
| His -42 | - | expression tag |
| His -41 | - | expression tag |
| His -40 | - | expression tag |
| His -39 | - | expression tag |
| His -38 | - | expression tag |
| His -37 | - | expression tag |
| Ser -36 | - | expression tag |
| Ser -35 | - | expression tag |
| Gly -34 | - | expression tag |
| Leu -33 | - | expression tag |
| Val -32 | - | expression tag |
| Pro -31 | - | expression tag |
| Arg -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ser -28 | - | expression tag |
| His -27 | - | expression tag |
| Met -26 | - | expression tag |
| Ala -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Met -23 | - | expression tag |
| Thr -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Gln -19 | - | expression tag |
| Gln -18 | - | expression tag |
| Met -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Arg -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Val -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Phe -8 | - | expression tag |
| Gln -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Trp -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 251 | Asn 251 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51277.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 247.3 | |
| All* | Total formula weight | 51524.4 |
