9L2N
Crystal structure of Cytochalasin D bound to a filamentous conformation actin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin, alpha skeletal muscle | polymer | 375 | 41875.6 | 1 | UniProt (P68139) Pfam (PF00022) | Gallus gallus (chicken) | Alpha-actin-1 |
| 2 | B (B) | Actin-binding protein fragmin P | polymer | 162 | 18210.4 | 1 | UniProt (Q94707) | Physarum polycephalum | |
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D, F, G (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H (A) | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate | non-polymer | 507.6 | 1 | Chemie (CY9) | |||
| 7 | I, J (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | K, L (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 9 | M, N (A, B) | water | water | 18.0 | 853 | Chemie (HOH) |
Sequence modifications
B: 1 - 160 (UniProt: Q94707)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ala 13 | Asn 13 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60086.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1448.3 | |
| All* | Total formula weight | 61534.4 |
