9L2K

The crystal structure of SFTSV Gn and SD22 antibody complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Envelopment polyprotein	polymer	344	37958.1	1	UniProt (A0A1S6K8S9) Pfam (PF07243)	Severe fever with thrombocytopenia syndrome virus (Severe fever with thrombocytopenia virus Huaiyangshan banyangvirus)	M polyprotein
2	B (H)	SD22 heavy chain	polymer	223	23785.5	1		Homo sapiens
3	C (L)	SD22 light chain	polymer	214	23487.0	1		Homo sapiens
4	D (B)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	E (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)

Sequence modifications

A: 19 - 338 (UniProt: A0A1S6K8S9)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Trp 3	-	expression tag
Ser 4	-	expression tag
Cys 5	-	expression tag
Ile 6	-	expression tag
Ile 7	-	expression tag
Leu 8	-	expression tag
Phe 9	-	expression tag
Leu 10	-	expression tag
Val 11	-	expression tag
Ala 12	-	expression tag
Thr 13	-	expression tag
Ala 14	-	expression tag
Thr 15	-	expression tag
Gly 16	-	expression tag
Val 17	-	expression tag
His 18	-	expression tag
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	85230.6
Branched	Number of molecules	2
	Total formula weight	1010.9
All*	Total formula weight	86241.6

*Water molecules are not included.