9L21
cryo-EM structure of Vitamin K-dependent gamma-carboxylase complexed with factor IX
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin K-dependent gamma-carboxylase | polymer | 698 | 81405.0 | 1 | UniProt (P38435) Pfam (PF05090) Pfam (PF22777) | Homo sapiens (human) | Gamma-glutamyl carboxylase,Peptidyl-glutamate 4-carboxylase,Vitamin K gamma glutamyl carboxylase |
| 2 | B (B) | Coagulation factor IX | polymer | 28 | 3338.8 | 1 | UniProt (P00740) | Homo sapiens (human) | Christmas factor,Plasma thromboplastin component,PTC |
| 3 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | F (A) | vitamin K1 hydroquinone | non-polymer | 452.7 | 1 | Chemie (A1AVC) | |||
| 6 | G (A) | BICARBONATE ION | non-polymer | 61.0 | 1 | Chemie (BCT) | |||
| 7 | H (A) | CARBON DIOXIDE | non-polymer | 44.0 | 1 | Chemie (CO2) | |||
| 8 | I (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 9 | J, K, M (A) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 3 | Chemie (PEE) | |||
| 10 | L (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
| 11 | N, O (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84743.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 3884.4 | |
| All* | Total formula weight | 89477.0 |
