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9L0S

Cryo-EM structure of human lipid phosphate phosphatase 1 complexed with VO4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(D, A, B, C)
Phospholipid phosphatase 1polymer28432193.04UniProt (O14494)
Pfam (PF01569)
Homo sapiens (human)Lipid phosphate phosphohydrolase 1,PAP2-alpha,Phosphatidate phosphohydrolase type 2a,Phosphatidic acid phosphatase 2a,PAP-2a,PAP2a
2E, K, P, U
(D, A, B, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
3F, L, Q, V
(D, A, B, C)
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholinenon-polymer760.14Chemie (LBN)
4G, M, R, W
(D, A, B, C)
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoatenon-polymer1047.14Chemie (PT5)
5H, N, S, X
(D, A, B, C)
VANADATE IONnon-polymer114.94Chemie (VO4)
6I, J, O, T
(D, A, B, C)
2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATEnon-polymer648.94Chemie (LPP)
7AA, BA, Y, Z
(B, C, D, A)
waterwater18.032Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight128772.1
Non-Polymers*Number of molecules20
Total formula weight11168.8
All*Total formula weight139940.9
*Water molecules are not included.

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PDB entries from 2026-01-28

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