9L06
The cryo-EM structure of ATRX in complex with the nucleosome in the ADP.BeFx-bound state (composite)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.3 | polymer | 136 | 15361.0 | 2 | UniProt (P84243) | Homo sapiens (human) | |
| 2 | B (B) | Histone H4 | polymer | 87 | 10004.8 | 1 | UniProt (P62805) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-C | polymer | 130 | 14135.5 | 2 | UniProt (Q93077) | Homo sapiens (human) | H2A-clustered histone 6,Histone H2A/l |
| 4 | D, H (D, H) | Histone H2B type 1-C/E/F/G/I | polymer | 126 | 13937.2 | 2 | UniProt (P62807) | Homo sapiens (human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
| 5 | F (F) | Histone H4 | polymer | 86 | 9861.6 | 1 | UniProt (P62805) | Homo sapiens (human) | |
| 6 | I (I) | DNA (207-MER) | polymer | 207 | 63673.6 | 1 | Homo sapiens | ||
| 7 | J (J) | DNA (207-MER) | polymer | 207 | 64144.9 | 1 | Homo sapiens | ||
| 8 | K (K) | Transcriptional regulator ATRX | polymer | 1260 | 143105.2 | 1 | UniProt (P46100) | Homo sapiens (human) | ATP-dependent helicase ATRX,X-linked helicase II,X-linked nuclear protein,XNP,Znf-HX |
| 9 | L (K) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 10 | M (K) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) |
Sequence modifications
K: 1251 - 2492 (UniProt: P46100)
| PDB | External Database | Details |
|---|---|---|
| Unk 1901 | Tyr 1901 | conflict |
| Unk 1902 | Phe 1902 | conflict |
| Unk 1903 | Asp 1903 | conflict |
| Unk 1904 | Glu 1904 | conflict |
| Unk 1905 | Asp 1905 | conflict |
| Unk 1906 | Ser 1906 | conflict |
| Unk 1907 | Met 1907 | conflict |
| Unk 1908 | Asp 1908 | conflict |
| Unk 1909 | Glu 1909 | conflict |
| Unk 1910 | Phe 1910 | conflict |
| Unk 1911 | Ile 1911 | conflict |
| Unk 1912 | Ala 1912 | conflict |
| Unk 1913 | Ser 1913 | conflict |
| Unk 1914 | Asp 1914 | conflict |
| Unk 1915 | Ser 1915 | conflict |
| Unk 1916 | Asp 1916 | conflict |
| Unk 1917 | Glu 1917 | conflict |
| Unk 1918 | Thr 1918 | conflict |
| Unk 1919 | Ser 1919 | conflict |
| Unk 1920 | Met 1920 | conflict |
| Unk 1921 | Ser 1921 | conflict |
| Unk 1922 | Leu 1922 | conflict |
| Unk 1923 | Ser 1923 | conflict |
| Unk 1924 | Ser 1924 | conflict |
| Unk 1925 | Asp 1925 | conflict |
| Unk 1926 | Asp 1926 | conflict |
| Unk 1927 | Tyr 1927 | conflict |
| Unk 1928 | Thr 1928 | conflict |
| Unk 1929 | Lys 1929 | conflict |
| Unk 1930 | Lys 1930 | conflict |
| Unk 1931 | Lys 1931 | conflict |
| Unk 1932 | Lys 1932 | conflict |
| Unk 1933 | Lys 1933 | conflict |
| Unk 1934 | Gly 1934 | conflict |
| Unk 1935 | Lys 1935 | conflict |
| Unk 1936 | Lys 1936 | conflict |
| Unk 1937 | Gly 1937 | conflict |
| Unk 1938 | Lys 1938 | conflict |
| Unk 1939 | Lys 1939 | conflict |
| Unk 1940 | Asp 1940 | conflict |
| Unk 1941 | Ser 1941 | conflict |
| Unk 1942 | Ser 1942 | conflict |
| Unk 1943 | Ser 1943 | conflict |
| Unk 1944 | Ser 1944 | conflict |
| Unk 1945 | Gly 1945 | conflict |
| Unk 1946 | Ser 1946 | conflict |
| Unk 1947 | Gly 1947 | conflict |
| Unk 1948 | Ser 1948 | conflict |
| Unk 1949 | Asp 1949 | conflict |
| Unk 1950 | Asn 1950 | conflict |
| Unk 1951 | Asp 1951 | conflict |
| Unk 1952 | Val 1952 | conflict |
| Unk 1953 | Glu 1953 | conflict |
| Unk 1954 | Val 1954 | conflict |
| Unk 1955 | Ile 1955 | conflict |
| Unk 1956 | Lys 1956 | conflict |
| Unk 1957 | Val 1957 | conflict |
| Unk 1958 | Trp 1958 | conflict |
| Unk 1959 | Asn 1959 | conflict |
| Unk 1960 | Ser 1960 | conflict |
| Unk 1961 | Arg 1961 | conflict |
| Unk 1962 | Ser 1962 | conflict |
| Unk 1963 | Arg 1963 | conflict |
| Unk 1964 | Gly 1964 | conflict |
| Unk 1965 | Gly 1965 | conflict |
| Unk 1966 | Gly 1966 | conflict |
| Unk 1967 | Glu 1967 | conflict |
| Unk 1968 | Gly 1968 | conflict |
| Unk 1969 | Asn 1969 | conflict |
| Unk 1970 | Val 1970 | conflict |
| Unk 1971 | Asp 1971 | conflict |
| Unk 1972 | Glu 1972 | conflict |
| Unk 1973 | Thr 1973 | conflict |
| Unk 1974 | Gly 1974 | conflict |
| Unk 1975 | Asn 1975 | conflict |
| Unk 1976 | Asn 1976 | conflict |
| Unk 1977 | Pro 1977 | conflict |
| Unk 1978 | Ser 1978 | conflict |
| Unk 1979 | Val 1979 | conflict |
| Unk 1980 | Ser 1980 | conflict |
| Unk 1981 | Leu 1981 | conflict |
| Unk 1982 | Lys 1982 | conflict |
| Unk 1983 | Leu 1983 | conflict |
| Unk 1984 | Glu 1984 | conflict |
| Unk 1985 | Glu 1985 | conflict |
| Unk 1986 | Ser 1986 | conflict |
| Unk 1987 | Lys 1987 | conflict |
| Unk 1988 | Ala 1988 | conflict |
| Unk 1989 | Thr 1989 | conflict |
| His 2493 | - | expression tag |
| His 2494 | - | expression tag |
| His 2495 | - | expression tag |
| His 2496 | - | expression tag |
| His 2497 | - | expression tag |
| His 2498 | - | expression tag |
| His 2499 | - | expression tag |
| His 2500 | - | expression tag |
| His 2501 | - | expression tag |
| His 2502 | - | expression tag |
| Asp 2503 | - | expression tag |
| Tyr 2504 | - | expression tag |
| Lys 2505 | - | expression tag |
| Asp 2506 | - | expression tag |
| Asp 2507 | - | expression tag |
| Asp 2508 | - | expression tag |
| Asp 2509 | - | expression tag |
| Lys 2510 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 377657.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 451.5 | |
| All* | Total formula weight | 378109.0 |
