9KZ3

PEDV 3CLpro mutant (C144A) in complex with nsp8|9 peptite substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ORF1ab polyprotein	polymer	310	33947.4	2	UniProt (A0A023J7B5) Pfam (PF05409)	Porcine epidemic diarrhea virus
2	C (C)	Replicase polyprotein 1a	polymer	6	758.0	1		Porcine epidemic diarrhea virus
3	D (D)	Replicase polyprotein 1a	polymer	6	758.0	1		Porcine epidemic diarrhea virus
4	E, F, G, H (A, B, C, D)	water	water		18.0	264	Chemie (HOH)

Sequence modifications

A, B: 1 - 299 (UniProt: A0A023J7B5)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 144	Cys 3141	engineered mutation
Leu 300	-	expression tag
Glu 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	69410.6
All*	Total formula weight	69410.6

*Water molecules are not included.