Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9KVI

A Cryo_EM structure of 5_HT1A complex with DMT

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440356.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34437784.31UniProt (P62873)
Pfam (PF25391)
Homo sapiens (human)Transducin beta chain 1
3C
(E)
SCFV16polymer24726277.31Homo sapiens (human)
4D
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
5E
(R)
5-hydroxytryptamine receptor 1Apolymer39843859.31UniProt (P08908)
Pfam (PF00001)
Homo sapiens (human)5-HT-1A,5-HT1A,G-21,Serotonin receptor 1A
6F
(R)
Bufoteninnon-polymer204.31Chemie (A1EG8)
7G
(R)
GLYCOCHENODEOXYCHOLIC ACIDnon-polymer449.61Chemie (CHO)
8H
(R)
CHOLESTEROLnon-polymer386.71Chemie (CLR)
9I
(R)
[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoatenon-polymer854.91Chemie (J40)
10J
(R)
waterwater18.07Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Asn 47Ser 47conflict
Ala 203Gly 203conflict
Asp 236Glu 236conflict
Glu 237Asp 237conflict
Ala 238Glu 238conflict
Ala 245Glu 245conflict
Ser 326Ala 326conflict
B: 7 - 345 (UniProt: P62873)
PDBExternal DatabaseDetails
Gly 2-expression tag
Ser 3-expression tag
Leu 4-expression tag
Leu 5-expression tag
Gln 6-expression tag
R: 25 - 422 (UniProt: P08908)
PDBExternal DatabaseDetails
Trp 125Leu 125conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight156138.0
Non-Polymers*Number of molecules4
Total formula weight1895.4
All*Total formula weight158033.5
*Water molecules are not included.

248335

PDB entries from 2026-01-28

PDB statisticsPDBj update infoContact PDBjnumon