9KV7

Cryo-EM structure of mouse RIPK1-DD filament

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, G, H, I, J...)	Receptor-interacting serine/threonine-protein kinase 1	polymer	120	13810.7	23	UniProt (Q60855) Pfam (PF00531)	Mus musculus (house mouse)	Cell death protein RIP,Receptor-interacting protein 1,RIP-1

Sequence modifications

A, G, H, I, J, K, B, C, D, E, F, L, P, R, V, X, M, Q, S, U, W, N, O: 568 - 656 (UniProt: Q60855)

PDB	External Database	Details
Met 537	-	initiating methionine
Gly 538	-	expression tag
Ser 539	-	expression tag
Ser 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
Ser 547	-	expression tag
Ser 548	-	expression tag
Gly 549	-	expression tag
Leu 550	-	expression tag
Val 551	-	expression tag
Pro 552	-	expression tag
Arg 553	-	expression tag
Gly 554	-	expression tag
Ser 555	-	expression tag
His 556	-	expression tag
Met 557	-	expression tag
Leu 558	-	expression tag
Glu 559	-	expression tag
Val 560	-	expression tag
Leu 561	-	expression tag
Phe 562	-	expression tag
Gln 563	-	expression tag
Gly 564	-	expression tag
Pro 565	-	expression tag
Val 566	-	expression tag
Asp 567	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	23
	Total formula weight	317645.4
All*	Total formula weight	317645.4

*Water molecules are not included.