9KU4
Cryo-EM structure of E373A mutant RIG-I with 5'p-RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Antiviral innate immune response receptor RIG-I | polymer | 925 | 106682.5 | 1 | UniProt (O95786) Pfam (PF16739) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) Pfam (PF11648) | Homo sapiens (human) | ATP-dependent RNA helicase DDX58,DEAD box protein 58,RIG-I-like receptor 1,RLR-1,RNA sensor RIG-I,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I |
| 2 | B (C) | RNA (60-MER) | polymer | 60 | 19242.4 | 1 | synthetic construct | ||
| 3 | C (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
B: 1 - 925 (UniProt: O95786)
| PDB | External Database | Details |
|---|---|---|
| Ala 373 | Glu 373 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 125924.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 125990.3 |
