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9KS9

Crystal structure of MerTK kinase domain in complex with compound 6

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tyrosine-protein kinase Merpolymer29433856.22UniProt (Q12866)
Pfam (PF07714)
Homo sapiens (human)Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK
2C, D
(A, B)
~{N}-[4-[5-(3-aminophenyl)-6-(1-methylpyrazol-4-yl)furo[2,3-d]pyrimidin-4-yl]oxyphenyl]-1-(4-fluorophenyl)-2-oxidanylidene-pyridine-3-carboxamidenon-polymer613.62Chemie (A1L6L)
3E, F
(A, B)
waterwater18.056Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67712.5
Non-Polymers*Number of molecules2
Total formula weight1227.2
All*Total formula weight68939.7
*Water molecules are not included.

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PDB entries from 2025-12-17

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