9KQN

Hsp90-Cdc37-PINK1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heat shock protein HSP 90-alpha	polymer	732	84781.7	2	UniProt (P07900) Pfam (PF13589) Pfam (PF00183)	Homo sapiens (human)	Heat shock 86 kDa,HSP 86,HSP86,Heat shock protein family C member 1,Lipopolysaccharide-associated protein 2,LAP-2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38
2	C (C)	Serine/threonine-protein kinase PINK1, mitochondrial	polymer	494	54081.1	1	UniProt (Q9BXM7) Pfam (PF00069)	Homo sapiens (human)	BRPK,PTEN-induced putative kinase protein 1
3	D (E)	Hsp90 co-chaperone Cdc37	polymer	378	44622.4	1	UniProt (Q16543) Pfam (PF03234) Pfam (PF08565) Pfam (PF08564)	Homo sapiens (human)	Hsp90 chaperone protein kinase-targeting subunit,p50Cdc37
4	E, F (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Sequence modifications

C: 110 - 581 (UniProt: Q9BXM7)

PDB	External Database	Details
Asp 582	-	expression tag
Tyr 583	-	expression tag
Lys 584	-	expression tag
Asp 585	-	expression tag
His 586	-	expression tag
Asp 587	-	expression tag
Gly 588	-	expression tag
Gly 589	-	expression tag
Tyr 590	-	expression tag
Lys 591	-	expression tag
Asp 592	-	expression tag
His 593	-	expression tag
Asp 594	-	expression tag
Ile 595	-	expression tag
Asp 596	-	expression tag
Tyr 597	-	expression tag
Lys 598	-	expression tag
Asp 599	-	expression tag
Asp 600	-	expression tag
Asp 601	-	expression tag
Asp 602	-	expression tag
Lys 603	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	268266.9
Non-Polymers*	Number of molecules	2
	Total formula weight	854.4
All*	Total formula weight	269121.3

*Water molecules are not included.