9KND

Crystal structure of human ERRg LBD in complex with indole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Estrogen-related receptor gamma	polymer	251	28386.9	1	UniProt (P62508) Pfam (PF00104)	Homo sapiens (human)	ERR gamma-2,Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3
2	B (B)	Nuclear receptor-interacting protein 1	polymer	15	1693.0	1	UniProt (P48552)	Homo sapiens (human)	Nuclear factor RIP140,Receptor-interacting protein 140
3	C (A)	INDOLE	non-polymer		117.1	1	Chemie (IND)
4	D, E (A, B)	water	water		18.0	312	Chemie (HOH)

Sequence modifications

A: 229 - 458 (UniProt: P62508)

PDB	External Database	Details
Met 208	-	initiating methionine
Gly 209	-	expression tag
Ser 210	-	expression tag
Ser 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
Ser 218	-	expression tag
Ser 219	-	expression tag
Gly 220	-	expression tag
Leu 221	-	expression tag
Val 222	-	expression tag
Pro 223	-	expression tag
Arg 224	-	expression tag
Gly 225	-	expression tag
Ser 226	-	expression tag
His 227	-	expression tag
Met 228	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30079.9
Non-Polymers*	Number of molecules	1
	Total formula weight	117.1
All*	Total formula weight	30197.1

*Water molecules are not included.