9KM7
Cryo-EM structure of glycine transporter 2 in complex with ORG25543
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transporter | polymer | 591 | 66663.4 | 1 | UniProt (A0A7D9NK84) Pfam (PF00209) | Xenopus tropicalis (tropical clawed frog) | |
| 2 | B (A) | ~{N}-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-phenylmethoxy-benzamide | non-polymer | 412.5 | 1 | Chemie (A1EF1) | |||
| 3 | C (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
A: 177 - 767 (UniProt: A0A7D9NK84)
| PDB | External Database | Details |
|---|---|---|
| Val 281 | Ile 281 | conflict |
| Ile 283 | Met 283 | conflict |
| Leu 319 | Met 319 | conflict |
| Asn 521 | His 521 | conflict |
| Glu 522 | Ile 522 | conflict |
| Arg 523 | Leu 523 | conflict |
| Lys 524 | Asn 524 | conflict |
| Asn 526 | Asp 526 | conflict |
| Asn 529 | Lys 529 | conflict |
| Phe 621 | Leu 621 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66663.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 799.2 | |
| All* | Total formula weight | 67462.5 |
