9KM6
The crystal structure of XhnM1 and its inhibitor sinefugin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Class I SAM-dependent methyltransferase | polymer | 304 | 32075.9 | 2 | UniProt (A0A3R7FZU3) Pfam (PF13649) | Streptomyces xinghaiensis | |
| 2 | C, I (A, B) | SINEFUNGIN | non-polymer | 381.4 | 2 | Chemie (SFG) | |||
| 3 | D, J, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | E, F, G, H (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 283 (UniProt: A0A3R7FZU3)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 215 | Val 215 | conflict |
| Val 240 | Ala 240 | conflict |
| Asp 264 | Glu 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64151.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1237.5 | |
| All* | Total formula weight | 65389.4 |
