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9KLB

G9a in complex with RK-133232 (compound 16g)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histone-lysine N-methyltransferase EHMT2polymer28332604.92UniProt (Q96KQ7)
Pfam (PF05033)
Pfam (PF00856)
Homo sapiens (human)Euchromatic histone-lysine N-methyltransferase 2,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3,H3-K9-HMTase 3,Lysine N-methyltransferase 1C,Protein G9a
2C, D, E, F, I...
(A, B)
ZINC IONnon-polymer65.48Chemie (ZN)
3G, M
(A, B)
SINEFUNGINnon-polymer381.42Chemie (SFG)
4H, N
(A, B)
~{N}-[(~{E},2~{S})-4-cyclopropyl-1-[(6-ethoxypyridin-3-yl)amino]-1-oxidanylidene-but-3-en-2-yl]-4-(pyridin-4-ylamino)benzamidenon-polymer457.52Chemie (A1L57)
5O, P
(A, B)
waterwater18.0233Chemie (HOH)
Sequence modifications
A, B: 913 - 1193 (UniProt: Q96KQ7)
PDBExternal DatabaseDetails
Gly 911-expression tag
Ser 912-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65209.8
Non-Polymers*Number of molecules12
Total formula weight2201.1
All*Total formula weight67410.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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