9KFT
Cryo-EM structure of the fMLFC-FPR1-Gi complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40374.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37415.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (R) | fMet-Leu-Phe receptor | polymer | 350 | 38477.3 | 1 | UniProt (P21462) Pfam (PF00001) | Homo sapiens (human) | fMLP receptor,N-formyl peptide receptor,FPR,N-formylpeptide chemoattractant receptor |
| 5 | E (S) | SCFV16 | polymer | 247 | 26337.3 | 1 | Vicugna pacos | ||
| 6 | F (L) | fMLFC peptide | polymer | 4 | 540.7 | 1 | Homo sapiens |
Sequence modifications
A: 2 - 354 (UniProt: P63096)
B: 1 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Cys 47 | Ser 47 | conflict |
| Thr 202 | Gly 202 | conflict |
| Ala 203 | Gly 203 | conflict |
| Ser 326 | Ala 326 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 172 | Glu 172 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 151006.4 | |
| All* | Total formula weight | 151006.4 |
