9KFL
KRAS G12V and peptide complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, D, E, H, K) | Isoform 2B of GTPase KRas | polymer | 168 | 19184.7 | 5 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | F, G (P, Y) | TIG3 peptide | polymer | 8 | 780.9 | 2 | UniProt (Q9UL19) | Homo sapiens | HRAS-like suppressor 4,HRSL4,RAR-responsive protein TIG3,Retinoic acid receptor responder protein 3,Retinoid-inducible gene 1 protein,Tazarotene-induced gene 3 protein,Phospholipase A and acyltransferase 4 |
| 3 | H, J, L, N, P (A, D, E, H, K) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 4 | I, K, M, O, Q (A, D, E, H, K) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 5 | Chemie (GDP) |
Sequence modifications
A, D, E, H, K: 1 - 168 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 97485.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2337.5 | |
| All* | Total formula weight | 99822.5 |
