9KDS
The crystal structure of human AURKA kinase domain in complex with RA1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aurora kinase A | polymer | 266 | 31387.4 | 1 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | Aurora 2,Aurora/IPL1-related kinase 1,ARK-1,Aurora-related kinase 1,Breast tumor-amplified kinase,Ipl1- and aurora-related kinase 1,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase Ayk1,Serine/threonine-protein kinase aurora-A |
| 2 | B (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 126 - 391 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Ala 290 | Cys 290 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31387.4 | |
| All* | Total formula weight | 31387.4 |
