9KCN

Cryo-EM structure of FD4-bound alpha-synuclein fibril polymorph 6A6B

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Alpha-synuclein	polymer	5	443.5	12		Homo sapiens
2	B, D, F, H, J... (L, M, N, P, Q...)	Alpha-synuclein	polymer	104	10820.8	12	UniProt (P37840) Pfam (PF01387)	Homo sapiens (human)	Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
3	AA, BA, CA, DA, EA... (M, N, P, d, e...)	(2~{R})-1-fluoranyl-3-[[2-[(~{E})-2-[5-[6-(methylamino)pyridin-3-yl]pyridin-2-yl]ethenyl]-1,3-benzothiazol-6-yl]oxy]propan-2-ol	non-polymer		436.5	12	Chemie (A1EFL)
4	AB, BB, CB, DB, EB... (W, f, Y, h, a...)	water	water		18.0	48	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	135172.5
Non-Polymers*	Number of molecules	12
	Total formula weight	5238.0
All*	Total formula weight	140410.5

*Water molecules are not included.