9KCG
Cryo-EM structure of human sodium pump WT in (3Na+)E1-AMPPCP state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/potassium-transporting ATPase subunit alpha-1 | polymer | 985 | 108781.0 | 1 | UniProt (P05023) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00689) | Homo sapiens (human) | Na(+)/K(+) ATPase alpha-1 subunit,Sodium pump subunit alpha-1 |
| 2 | B (B) | Sodium/potassium-transporting ATPase subunit beta-3 | polymer | 279 | 31545.5 | 1 | UniProt (P54709) Pfam (PF00287) | Homo sapiens (human) | Sodium/potassium-dependent ATPase subunit beta-3,ATPB-3 |
| 3 | C (C) | FXYD domain-containing ion transport regulator 5 | polymer | 178 | 19492.8 | 1 | UniProt (Q96DB9) Pfam (PF02038) | Homo sapiens (human) | Dysadherin |
| 4 | D, E, F (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H, K, O (A, B) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 7 | I (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 8 | J, N (A, B) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 9 | L, M (A, B) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 2 | Chemie (PCW) | |||
| 10 | P (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 159819.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4913.0 | |
| All* | Total formula weight | 164732.3 |
