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9KBD

Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO3 SCF ubiquition ligase complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
S-phase kinase-associated protein 1polymer16318680.01UniProt (P63208)
Pfam (PF03931)
Pfam (PF01466)
Homo sapiens (human)Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1
2B
(C)
F-box only protein 3polymer43650305.61UniProt (Q9UK99)
Pfam (PF00646)
Pfam (PF09346)
Pfam (PF04379)
Homo sapiens (human)
3C
(R)
E3 ubiquitin-protein ligase RBX1polymer10812290.01UniProt (P62877)
Pfam (PF12678)
Homo sapiens (human)E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1
4D
(A)
Cullin-1polymer77689800.41UniProt (Q13616)
Pfam (PF00888)
Pfam (PF10557)
Homo sapiens (human)CUL-1
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight171075.9
All*Total formula weight171075.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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