9K9N
Cryo-EM structure of MjHKU4r-CoV-1 receptor-binding domain complexed with human CD26
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dipeptidyl peptidase 4 soluble form | polymer | 766 | 88445.4 | 2 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (human) | Dipeptidyl peptidase IV soluble form |
| 2 | C (C) | Spike protein S1 | polymer | 231 | 25607.3 | 1 | UniProt (A0AAE8ZFM2) Pfam (PF09408) UniProt (by SIFTS) (A3EX94) | Tylonycteris bat coronavirus HKU4 | S glycoprotein,E2,Peplomer protein |
| 3 | D, E, F, I (D, E, F, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G (G) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
| 5 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 6 | J, K, L, M, N... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) |
Sequence modifications
A, B: 39 - 766 (UniProt: P27487)
C: 389 - 595 (UniProt: A0AAE8ZFM2)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | initiating methionine |
| Gly 8 | - | expression tag |
| Ile 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Pro 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Met 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Val 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Leu 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Val 27 | - | expression tag |
| Leu 28 | - | expression tag |
| Leu 29 | - | expression tag |
| Met 30 | - | expression tag |
| Gly 31 | - | expression tag |
| Cys 32 | - | expression tag |
| Val 33 | - | expression tag |
| Ala 34 | - | expression tag |
| Glu 35 | - | expression tag |
| Thr 36 | - | expression tag |
| Gly 37 | - | expression tag |
| Thr 38 | - | expression tag |
| His 767 | - | expression tag |
| His 768 | - | expression tag |
| His 769 | - | expression tag |
| His 770 | - | expression tag |
| His 771 | - | expression tag |
| His 772 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 371 | - | initiating methionine |
| His 372 | - | expression tag |
| Ser 373 | - | expression tag |
| Ser 374 | - | expression tag |
| Ala 375 | - | expression tag |
| Leu 376 | - | expression tag |
| Leu 377 | - | expression tag |
| Cys 378 | - | expression tag |
| Cys 379 | - | expression tag |
| Leu 380 | - | expression tag |
| Val 381 | - | expression tag |
| Leu 382 | - | expression tag |
| Leu 383 | - | expression tag |
| Thr 384 | - | expression tag |
| Gly 385 | - | expression tag |
| Val 386 | - | expression tag |
| Arg 387 | - | expression tag |
| Ala 388 | - | expression tag |
| Ala 482 | Ser 482 | conflict |
| Glu 544 | Val 544 | conflict |
| His 596 | - | expression tag |
| His 597 | - | expression tag |
| His 598 | - | expression tag |
| His 599 | - | expression tag |
| His 600 | - | expression tag |
| His 601 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 202498.0 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3179.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 207889.0 |
