9K93

Cryo-EM structure of human signal peptide peptidase like 2A (SPPL2a) in complex with L685,458

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Signal peptide peptidase-like 2A	polymer	520	58189.8	1	UniProt (Q8TCT8)	Homo sapiens (human)	SPP-like 2A,SPPL2a,Intramembrane protease 3,IMP-3,Presenilin-like protein 2
2	B (A)	~{tert}-butyl ~{N}-[(2~{S},3~{R},5~{R})-6-[[(2~{S})-1-[[(2~{S})-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-oxidanyl-6-oxidanylidene-1-phenyl-5-(phenylmethyl)hexan-2-yl]carbamate	non-polymer		672.9	1	Chemie (FTO)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58189.8
Non-Polymers*	Number of molecules	1
	Total formula weight	672.9
All*	Total formula weight	58862.7

*Water molecules are not included.