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9K8W

Crystal structure of the calcium indicator GCaMP6s-BrUS in calcium-bound state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Calcium indicator GCaMP6s-BrUS,Calmodulin-1polymer46352032.11UniProt (P0DP23)
Pfam (PF01353)
Pfam (PF13499)
UniProt (by SIFTS) (P42212)
synthetic construct
2B, C, D, E
(A)
CALCIUM IONnon-polymer40.14Chemie (CA)
3F
(A)
waterwater18.090Chemie (HOH)
Sequence modifications
A: 1 - 315 (PDB: 9K8W)
A: 316 - 463 (UniProt: P0DP23)
PDBExternal DatabaseDetails
Pro 316Ala 2engineered mutation
Asp 375Asn 61engineered mutation
Tyr 393Asp 79engineered mutation
Arg 394Thr 80engineered mutation
Thr 396Ser 82engineered mutation
Gly 405Arg 91engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52032.1
Non-Polymers*Number of molecules4
Total formula weight160.3
All*Total formula weight52192.4
*Water molecules are not included.

236620

PDB entries from 2025-05-28

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