9K7B
Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium- and chloride-dependent taurine transporter | polymer | 632 | 71211.0 | 1 | UniProt (P31641) Pfam (PF00209) | Homo sapiens (human) | Solute carrier family 6 member 6 |
| 2 | B, C, D, E (A) | 2-AMINOETHANESULFONIC ACID | non-polymer | 125.1 | 4 | Chemie (TAU) | |||
| 3 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | H, I, J, K, L (A) | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 6 | M (A) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 1 - 620 (UniProt: P31641)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | initiating methionine |
| Asp -10 | - | expression tag |
| Tyr -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 71211.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2492.3 | |
| All* | Total formula weight | 73703.3 |
