9K34
Human IgG1 Fc fragments, mutant (2CT1.9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Immunoglobulin gamma-1 heavy chain | polymer | 223 | 25399.7 | 4 | UniProt (P0DOX5) | Homo sapiens (human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | E (E) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1641.5 | 1 | In PDB GlyTouCan (G36191CD) | |||
| 3 | F, H (F, H) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 2 | In PDB GlyTouCan (G89993FE) | |||
| 4 | G (G) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1787.6 | 1 | In PDB GlyTouCan (G23770JR) | |||
| 5 | I (A) | beta-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUL) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 228 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Arg 137 | Asp 358 | conflict |
| Trp 139 | Leu 360 | conflict |
| Arg 140 | Thr 361 | conflict |
| Glu 142 | Asn 363 | conflict |
| Glu 143 | Gln 364 | conflict |
| Glu 194 | Asp 415 | conflict |
| Ala 195 | Lys 416 | conflict |
| Trp 199 | Gln 420 | conflict |
| Trp 220 | Lys 441 | conflict |
| Arg 224 | Leu 445 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101599.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 6387.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 164.2 | |
| All* | Total formula weight | 108151.0 |
