9K2Y
Human IgG1 Fc fragments, mutant (2CT1.1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, A, B, D) | Immunoglobulin gamma-1 heavy chain | polymer | 223 | 25244.5 | 4 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | E, G (G, F) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1787.6 | 2 | In PDB GlyTouCan (G23770JR) | |||
| 3 | F (E) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 1 | In PDB GlyTouCan (G89993FE) | |||
| 4 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 951.9 | 1 | In PDB GlyTouCan (G12045WP) | |||
| 5 | I (I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G85856KC) | |||
| 6 | J (D) | beta-D-galactopyranose | non-polymer | 180.2 | 1 | Chemie (GAL) |
Sequence modifications
C, A, B, D: 6 - 228 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Trp 136 | Arg 357 | conflict |
| Arg 139 | Leu 360 | conflict |
| Glu 142 | Asn 363 | conflict |
| Glu 143 | Gln 364 | conflict |
| Glu 194 | Asp 415 | conflict |
| Ala 195 | Lys 416 | conflict |
| Trp 199 | Gln 420 | conflict |
| Arg 224 | Leu 445 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100978.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 6389.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 180.2 | |
| All* | Total formula weight | 107548.1 |
