9K1L

Complex structure of CNK2 and SAMD12

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Connector enhancer of kinase suppressor of ras 2	polymer	319	35486.6	1	UniProt (Q80YA9) Pfam (PF00536) Pfam (PF10534) Pfam (PF00595)	Mus musculus (house mouse)	Connector enhancer of KSR 2,CNK homolog protein 2,CNK2
2	B (B)	Sterile alpha motif domain-containing protein 12	polymer	98	11356.9	1	UniProt (Q0VE29) Pfam (PF07647)	Mus musculus (house mouse)	SAM domain-containing protein 12
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D, E (A, B)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A: 1 - 314 (UniProt: Q80YA9)

PDB	External Database	Details
Gly -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 78 - 161 (UniProt: Q0VE29)

PDB	External Database	Details
Gly 74	-	expression tag
Pro 75	-	expression tag
Gly 76	-	expression tag
Ser 77	-	expression tag
Gly 162	-	expression tag
Ser 163	-	expression tag
Gly 164	-	expression tag
Ser 165	-	expression tag
Glu 166	-	expression tag
Asn 167	-	expression tag
Leu 168	-	expression tag
Tyr 169	-	expression tag
Phe 170	-	expression tag
Gln 171	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46843.5
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	46935.6

*Water molecules are not included.