9JY0
Fab-CD3-gamma epsilon-TCR complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (a, b) | T-cell surface glycoprotein CD3 zeta chain | polymer | 166 | 18881.6 | 2 | UniProt (P20963) Pfam (PF11628) Pfam (PF02189) | Homo sapiens (human) | T-cell receptor T3 zeta chain |
| 2 | C (d) | T-cell surface glycoprotein CD3 delta chain | polymer | 171 | 18949.5 | 1 | UniProt (P04234) Pfam (PF16680) Pfam (PF02189) | Homo sapiens (human) | T-cell receptor T3 delta chain |
| 3 | D, G (e, f) | T-cell surface glycoprotein CD3 epsilon chain | polymer | 207 | 23174.2 | 2 | UniProt (P07766) Pfam (PF16681) Pfam (PF02189) | Homo sapiens (human) | T-cell surface antigen T3/Leu-4 epsilon chain |
| 4 | E (m) | T cell receptor delta variable 2,T cell receptor delta constant | polymer | 292 | 32662.7 | 1 | UniProt (A0JD36) UniProt (B7Z8K6) UniProt (by SIFTS) (B7Z8B9) | Homo sapiens (human) | |
| 5 | F (n) | T cell receptor gamma variable 9,T cell receptor gamma constant 1 | polymer | 315 | 35395.8 | 1 | UniProt (Q99603) UniProt (P0CF51) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (human) | TCR gamma |
| 6 | H (g) | T-cell surface glycoprotein CD3 gamma chain | polymer | 182 | 20493.5 | 1 | UniProt (P09693) Pfam (PF16680) Pfam (PF02189) | Homo sapiens (human) | T-cell receptor T3 gamma chain |
| 7 | I (A) | Fab light chain | polymer | 212 | 23475.9 | 1 | Homo sapiens | ||
| 8 | J (B) | Fab heavy chain | polymer | 222 | 24003.0 | 1 | Homo sapiens | ||
| 9 | K (m) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
a, b: 1 - 164 (UniProt: P20963)
m: -1 - 113 (UniProt: A0JD36)
m: 138 - 290 (UniProt: B7Z8K6)
n: -17 - 103 (UniProt: Q99603)
n: 125 - 297 (UniProt: P0CF51)
| PDB | External Database | Details |
|---|---|---|
| Ser 165 | - | expression tag |
| Ala 166 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 114 | - | linker |
| Gly 115 | - | linker |
| Met 116 | - | linker |
| Gly 117 | - | linker |
| Gly 118 | - | linker |
| Glu 119 | - | linker |
| Tyr 120 | - | linker |
| Thr 121 | - | linker |
| Asp 122 | - | linker |
| Lys 123 | - | linker |
| Leu 124 | - | linker |
| Ile 125 | - | linker |
| Phe 126 | - | linker |
| Gly 127 | - | linker |
| Lys 128 | - | linker |
| Gly 129 | - | linker |
| Thr 130 | - | linker |
| Arg 131 | - | linker |
| Val 132 | - | linker |
| Thr 133 | - | linker |
| Val 134 | - | linker |
| Glu 135 | - | linker |
| Pro 136 | - | linker |
| Arg 137 | - | linker |
n: -17 - 103 (UniProt: Q99603)
| PDB | External Database | Details |
|---|---|---|
| Ala 104 | - | linker |
| Gln 105 | - | linker |
| Gln 106 | - | linker |
| Glu 107 | - | linker |
| Leu 108 | - | linker |
| Gly 109 | - | linker |
| Lys 110 | - | linker |
| Lys 111 | - | linker |
| Ile 112 | - | linker |
| Lys 113 | - | linker |
| Val 114 | - | linker |
| Phe 115 | - | linker |
| Gly 116 | - | linker |
| Pro 117 | - | linker |
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Lys 120 | - | linker |
| Leu 121 | - | linker |
| Ile 122 | - | linker |
| Ile 123 | - | linker |
| Thr 124 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 171 | Gln 47 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 239092.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 239478.6 |
