9JWV
Structure of WDR5 Y191F in complex with WIN motif containing Kif2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | WD repeat-containing protein 5 | polymer | 315 | 34630.3 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | B, D (C, D) | Kinesin-like protein KIF2A | polymer | 9 | 931.0 | 2 | UniProt (O00139) | Homo sapiens (human) | Kinesin-2,hK2 |
| 3 | E, F, G, H (A, C, B, D) | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| Met 23 | - | expression tag |
| Phe 191 | Tyr 191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71122.6 | |
| All* | Total formula weight | 71122.6 |
