9JTX
Factor inhibiting HIF-1 alpha in complex with Zn(II) and 2-(4-hydroxy-2-oxo-1-(thiazol-4-ylmethoxy)-1,2-dihydroquinoline-3-carboxamido)-2-methylpropanoic acid
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
2 | B, C, D, G, H... (A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
3 | E (A) | 2-methyl-2-[[4-oxidanyl-2-oxidanylidene-1-(1,3-thiazol-4-ylmethoxy)quinolin-3-yl]carbonylamino]propanoic acid | non-polymer | 403.4 | 1 | Chemie (A1L4V) | |||
4 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | K (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40328.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1141.3 | |
All* | Total formula weight | 41469.5 |