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9JTX

Factor inhibiting HIF-1 alpha in complex with Zn(II) and 2-(4-hydroxy-2-oxo-1-(thiazol-4-ylmethoxy)-1,2-dihydroquinoline-3-carboxamido)-2-methylpropanoic acid

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer34940328.31UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (human)Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase
2B, C, D, G, H...
(A)
SULFATE IONnon-polymer96.17Chemie (SO4)
3E
(A)
2-methyl-2-[[4-oxidanyl-2-oxidanylidene-1-(1,3-thiazol-4-ylmethoxy)quinolin-3-yl]carbonylamino]propanoic acidnon-polymer403.41Chemie (A1L4V)
4F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5K
(A)
waterwater18.058Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40328.3
Non-Polymers*Number of molecules9
Total formula weight1141.3
All*Total formula weight41469.5
*Water molecules are not included.

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PDB entries from 2025-05-28

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