9JS9
Crystal structure of the CYP154C5 F92A/R114A/T248G/E282A variant from Nocardia farcinica
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Cytochrome P450 monooxygenase | polymer | 429 | 47126.7 | 1 | UniProt (Q5YNS8) Pfam (PF00067) | Nocardia farcinica IFM 10152 | |
| 2 | B (B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (B) | TESTOSTERONE | non-polymer | 288.4 | 1 | Chemie (TES) PubChem (16220011) PubChem (16758160) PubChem (19615208) PubChem (20848917) PubChem (5408) PubChem (3034651) PubChem (6013) PubChem (242356) PubChem (369323) PubChem (40469851) PubChem (40785049) PubChem (40785050) PubChem (638016) PubChem (711503) PubChem (51508681) PubChem (908606) PubChem (908608) PubChem (1312122) PubChem (57094693) PubChem (57185304) PubChem (58483165) PubChem (59847731) PubChem (59859271) PubChem (70987786) PubChem (70987811) PubChem (71045973) PubChem (71051775) PubChem (71085514) PubChem (143796510) PubChem (5701998) PubChem (2825665) PubChem (6432567) PubChem (10204) PubChem (51519) PubChem (6541863) PubChem (6954100) PubChem (6954101) PubChem (6976807) PubChem (7048589) PubChem (7213985) PubChem (7213991) PubChem (71045971) PubChem (7985137) PubChem (10108190) PubChem (908607) PubChem (11861311) PubChem (11862155) PubChem (11869421) PubChem (11869422) PubChem (11869423) PubChem (11870497) PubChem (11890585) PubChem (11890586) PubChem (11920270) PubChem (12304591) PubChem (12304592) PubChem (6925433) PubChem (6994116) PubChem (117072371) PubChem (121384949) PubChem (12304594) PubChem (12304595) PubChem (124711639) PubChem (124711640) PubChem (126527172) PubChem (133562488) PubChem (135012819) PubChem (139228436) PubChem (141791996) PubChem (142296689) PubChem (142774791) PubChem (143701725) PubChem (155332323) PubChem (162460416) PubChem (162931702) PubChem (163788316) PubChem (169085516) | |||
| 4 | D (B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
B: 1 - 409 (UniProt: Q5YNS8)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 92 | Phe 92 | engineered mutation |
| Ala 114 | Arg 114 | engineered mutation |
| Gly 248 | Thr 248 | engineered mutation |
| Ala 282 | Glu 282 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47126.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 904.9 | |
| All* | Total formula weight | 48031.6 |
