9JRK
outward-open hSLC19A1 + MTX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Soluble cytochrome b562,Reduced folate transporter,fusion protein | polymer | 690 | 77520.0 | 1 | UniProt (P0ABE7) UniProt (P41440) Pfam (PF01770) | Escherichia coli | Cytochrome b-562,FOLT,Cyclic dinucleotide:anion antiporter SLC19A1,Folate:anion antiporter SLC19A1,Intestinal folate carrier 1,IFC-1,Placental folate transporter,Reduced folate carrier protein,RFC,hRFC,Reduced folate transporter 1,RFT-1,Solute carrier family 19 member 1,hSLC19A1 |
| 2 | B (A) | METHOTREXATE | non-polymer | 454.4 | 1 | Chemie (MTX) |
Sequence modifications
A: -82 - 23 (UniProt: P0ABE7)
A: 24 - 457 (UniProt: P41440)
A: 458 - 606 (PDB: 9JRK)
| PDB | External Database | Details |
|---|---|---|
| Met -83 | - | initiating methionine |
| Trp -76 | Met 29 | conflict |
| Ile 19 | His 124 | conflict |
| Leu 23 | Arg 128 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 58 | Asn 58 | conflict |
| Trp 307 | Gly 307 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 77520.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 454.4 | |
| All* | Total formula weight | 77974.4 |
