9JOR

structure of phage T4 topoisomerase II central domain bound with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, D)	DNA topoisomerase medium subunit	polymer	452	51952.0	2	UniProt (P07065)	Escherichia phage T4 (Bacteriophage T4)	Topo II gp52 subunit,DNA topoisomerase 51-kDa subunit,Protein Gp52
2	B, D (A, B)	DNA topoisomerase large subunit,DNA topoisomerase small subunit	polymer	682	77524.7	2	UniProt (P09176) UniProt (P23992)	Escherichia phage T4 (Bacteriophage T4)	Topo II gp39 subunit,DNA topoisomerase 64-kDa subunit,Protein Gp39,Topo II gp60 subunit,DNA topoisomerase 18-kDa subunit,Protein Gp60
3	E (E)	DNA (5'-D(P*TP*GP*TP*GP*TP*GP*TP*AP*TP*AP*TP*AP*TP*AP*CP*AP*CP*AP*TP*AP*TP*AP*TP*A)-3')	polymer	24	7381.8	1		Homo sapiens
4	F (F)	DNA (5'-D(P*AP*TP*AP*TP*AP*TP*GP*TP*GP*TP*AP*TP*AP*TP*AP*TP*AP*CP*AP*CP*AP*CP*AP*T)-3')	polymer	24	7350.8	1		Homo sapiens
5	G, H, I (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)

Sequence modifications

C, D: 1 - 442 (UniProt: P07065)

PDB	External Database	Details
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
His 446	-	expression tag
His 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag

A, B: 1 - 516 (UniProt: P09176)
A, B: 517 - 676 (UniProt: P23992)

PDB	External Database	Details
His 677	-	expression tag
His 678	-	expression tag
His 679	-	expression tag
His 680	-	expression tag
His 681	-	expression tag
His 682	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	273686.0
Non-Polymers*	Number of molecules	3
	Total formula weight	72.9
All*	Total formula weight	273758.9

*Water molecules are not included.