9JN9

Cryo-EM structure of human SLFN14

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein SLFN14	polymer	921	104826.3	2	UniProt (P0C7P3) Pfam (PF17057) Pfam (PF04326) Pfam (PF21026)	Homo sapiens (human)
2	C, D (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, B: 1 - 912 (UniProt: P0C7P3)

PDB	External Database	Details
Gly -8	-	expression tag
Pro -7	-	expression tag
His -6	-	expression tag
Met -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Ala 206	Glu 206	engineered mutation
Ala 211	Glu 211	engineered mutation
Ser 356	Pro 356	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	209652.6
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	209783.4

*Water molecules are not included.